Endocrine Abstracts

73 year old lady with metastatic pancreatic cancer referred to diabetes clinic with worsening of her diabetes control. She was primarily under care of Gastroenterology department, for her symptoms of weight loss, abdominal pain, diarrhoea, sweating and anaemia. Her scan showed metastatic pancreatic cancer arising from tail of pancreatic with metastasis to liver. The liver biopsy of secondary liver deposit was not conclusive. She had borderline diabetes at her presentation wors...

A 61-year-old ex-smoker with a background of chronic obstructive pulmonary disease, bilateral cataracts and advanced retinitis pigmentosa presented in April 2014 with a 5 months history of feeling generally unwell and weight loss. He was found thyrotoxic with TSH suppressed to less than 0.01 mU/l, free T4 of 38 pmol/l and free T3 of 26 pmol/l. On examination there was tunnel vision bilaterally and diplopia in all directions with no evidence of thyroid eye...

Objective: Amiodarone is an iodine rich, potent antiarrhythmic drug that is highly lipid soluble and total body iodine stores remain increased for up to 9 months. Abnormal thyroid functions, either thyrotoxicosis or hypothyroidism occur in upto 14–18% of patients receiving long-term amiodarone therapy. Hence regular thyroid function tests are required in patients on long-term amiodarone treatment. The BNF clearly states that thyroid function tests should be done at a mini...

We describe a case of a male who presented to a rheumatologist with hypercalceamia at the age of 22 in 1995. Investigations were incomplete and he was lost to follow up. He was referred to a general surgeon in 2002 as another blood test had showed hypercalcaemia of 2.8 mmol/l (2.2–2.6), parathyroid hormone 9.5 pmol/l (1.6–6.9). A spot urine calcium/creatinine excretion ratio was 0.014. It was felt he probably had primary hyperparathyroidism and he was managed conserv...